Aug 2026
Targeting Mitochondrial Complex I Protects Against Palmitic Acid-Induced Endothelial Dysfunction.
BACKGROUND Endothelial dysfunction induced by elevated free fatty acids is a critical initiating event in diabetic macrovascular complications. While mitochondrial reactive oxygen species (mtROS) are key mediators of this lipotoxic injury, the specific contribution of mitochondrial Complex I dynamics and its associated...
Chen-Xia Zhou, Da Chen, Ruoxuan Li et al.
· Diabetes, obesity and metabo... · 0 citations