Open access
Aug 2026
Functional characterization of the Est-type macrolide esterase ECO-1 from Escherichia coli
Macrolides are widely used in both human and veterinary medicine, and enzymatic inactivation represents an important yet underexplored resistance mechanism beyond the well-studied Ere family. Here, we functionally characterized ECO-1, an Est-type macrolide esterase identified from Escherichia coli . Phylogenetic...
Tao Song, Xin-Yu Ye, Ya-Ni He et al.
· Scientific Reports · 0 citations