Integrative single‑cell and bulk transcriptomic profiling reveals MMP1 as a core effector and CTSB as a putative collaborator in ATBC‑aggravated pulmonary fibrosis.
BACKGROUND Acetyl tributyl citrate (ATBC) is a widely used environmentally friendly plasticizer, and exposure via the respiratory tract is common in the general population. However, its pulmonary toxicity and underlying molecular mechanisms remain poorly understood. METHODS An integrative strategy combining compound...