This study conducted a nationwide single-mosquito meta-transcriptomic survey of 5,163 mosquitoes representing 100 species across China, integrating viral discovery with marker-gene profiling of bacteria, archaea, fungi, and other eukaryotic microbes to establish a detailed view of the full-spectrum microbiome.
Qin-yu Gou, Wei-Chen Wu, Pei-Bo Shi et al.· bioRxiv· 0 citations
The results identified a key amino acid associated with viral recombination in NADC30-like PRRSV-2 and provide an editing target for developing safer vaccines that are less prone to recombination.