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Xinyuan Guan

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Open access Sep 2026

SNX9 Orchestrates Lung Metastasis via EGFR-ERK Signaling and Actin Cytoskeleton Remodeling in Breast Cancer

Objectives: Sorting nexin 9 (SNX9) participates in endocytic trafficking and has been connected to several malignancies, but its involvement in breast cancer (BC) remains incompletely resolved. This work was designed to examine whether SNX9 supports BC progression and investigate signaling and cytoskeletal processes as...

Qingqing Liu, Lei Li, Kumar Ganesan et al. · 0 citations
Preprint Aug 2026

EgoAfford: Task-Oriented Affordance Grounding via Egocentric Referring Segmentation

EgoAfford is introduced, a benchmark designed to connect the semantic roles of participating objects with task-state-aligned visual observations and multi-step planning and EgoLens, a 3B multimodal large language model with role-specific mask decoders, as an in-domain reference model for this joint task.

Xinyuan Guan, Feifan Chen, Xinyu Zhan et al. · 0 citations

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