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Author

Xinyue Yu

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Review Open access Jul 2026

Protein lactylation in cancer: principles, programmes and therapeutic opportunities.

Inhibition of lactate metabolism markedly attenuates tumor-associated lactylation and exhibits substantial synergistic efficacy when combined with other anti-tumor therapies, providing an important conceptual and theoretical foundation for the development of novel cancer therapeutic strategies targeting protein lactyla...

X. Bu, Xinyue Yu, Jie Wang et al. · 1 citation
Review Open access Jul 2026

Regulatory role of protein lactylation in tumor metastasis: mechanisms and emerging therapeutic strategies.

This review discusses how lactylation operates within a broader post-translational modification (PTM) network through crosstalk with acetylation, ubiquitination, and RNA methylation to amplify oncogenic signaling.

Xinyue Yu, Si-Wei Song, Yingji Ke et al. · 1 citation

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