Xiu-Feng Sun

Spatiotemporal mapping reveals microbiota-dependent maintenance of functional competence during postnatal immune maturation.

Postnatal immune maturation is commonly viewed as a developmental milestone associated with weaning. However, how postnatal microbiota exposure shapes immune cell heterogeneity across tissues, and whether this maturation is self-sustaining or requires continuous microbial input, remain unclear. Here, we conducted spati...