Xiu-Feng Yu

FOXC1 Drives Pulmonary Arterial Endothelial Cell Dysfunction and Vascular Remodeling through Transcriptional Activation of MACC1.

BACKGROUND Pulmonary arterial hypertension (PAH) is a progressive vascular disorder characterized by pulmonary vascular remodeling and endothelial dysfunction. Although several molecular regulators have been implicated in PAH pathogenesis, the key transcriptional networks governing these processes remain incompletely u...