Author

Xiu-Lan Sun

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Sep 2026

Photoactivatable NPOM-caged split-activator CRISPR/Cas12a biosensor for amplification-free imaging of deoxynivalenol-induced miR-155 dynamics and lateral-flow sensing.

MicroRNA-155 (miR-155) is an immune-associated small RNA biomarker involved in macrophage responses to environmental stressors such as deoxynivalenol (DON). However, achieving amplification-free miRNA sensing with low background and precise temporal regulation remains challenging. Here, we develop a photoactivatable sp...

Kuan-Wen Chang, Jia-Di Sun, Tao Liu et al. · Biosensors & bioelectronics · 0 citations

Sep 2026

Rational design of heptaprenyl diphosphate synthase and metabolic optimization drive biosynthesis of menaquinone-7 by Escherichia coli.

Menaquinone-7 (MK-7) is a fat-soluble vitamin with important nutritional and pharmaceutical applications. However, microbial biosynthesis of MK-7 is limited by low catalytic efficiency of key enzymes, insufficient precursor supply, and imbalanced availability of nicotinamide adenine dinucleotide phosphate (NADPH). In t...

Zi-Hao Li, Kang-Jie Xu, Yi-Yi Chen et al. · Bioresource Technology · 0 citations

2026

Interactive effects of temperature and water activity on growth, mycotoxin production, and transcriptomic profiles of Aspergillus flavus, Aspergillus parasiticus, and Fusarium verticillioides.

In vitro stress responses of Aspergillus flavus, Aspergillus parasiticus, and Fusarium verticillioides are investigated across broad gradients of temperature and water activity to provide a theoretical basis for developing targeted mycotoxin mitigation strategies under environmental factors change.

Xiyu Cao, Xuran Fu, Jiadi Sun et al. · Food microbiology · 0 citations