Sirtuins, which comprise a family of NAD+-dependent deacetylases, have emerged as critical regulators in the pathogenesis of pulmonary diseases because of their pleiotropic roles in oxidative stress, metabolic homeostasis and inflammation. Growing evidence indicates that sirtuins modulate key cellular processes, includ...
Shuangyun Xi, Weijun Chen, Xiu-Li Li et al.· International Journal of Mol...· 0 citations
Functional analysis of all 65 variants revealed that ion channel genes and neurodevelopmental genes were the most frequently affected categories, and whole-exome sequencing identified clinically relevant genetic findings in a subset of Southeast Chinese children with seizure disorders.
Shan Hong, Dan-Dan Han, Ming Qi et al.· Annals of Medicine and Surge...· 0 citations
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