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Xiu-Qiang Yu

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Open access Sep 2026

Food derived raffinose attenuates cyclophosphamide-induced immunosuppression in mice with associated changes in gut microbiota, short-chain fatty acids and intestinal barrier integrity.

BACKGROUND Cyclophosphamide (CTX)-induced immunosuppression is accompanied by systemic immune impairment and intestinal dysbiosis. This study evaluated whether raffinose (Raf), a food-derived prebiotic trisaccharide, is associated with improved immune and intestinal outcomes during CTX challenge. RESULTS Forty male I...

Peng Zhang, Tian-Yi Zhang, Qi-Cheng Lu et al. · 0 citations

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