Author

Xiu-Qing Guo

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Open access Oct 2026

Age‐Specific Associations of Polygenic Risk Scores With Advanced Fibrosis and Histological Activity in Biopsy‐Proven MASLD

ABSTRACT Background and Aims The genetic susceptibility to MASLD histological severity remains incompletely defined. We assessed the associations between recently developed genome‐wide association studies–derived polygenic risk scores (PRSs) and advanced fibrosis in MASLD. We also evaluated PRSs' associations with hist...

S. Gawrieh, Jing-Yi Tan, Xiu-Qing Guo et al. · Liver international (Print) · 0 citations

Open access Jul 2026

Using Polygenic Risk Scores to Evaluate Definitions of Self-Reported Sleep Phenotypes Across Cohorts.

Which sleep PRS performed well across diverse populations and which sleep definitions better captured genetic underpinnings was highlighted by evaluating several types of sleep PRSs and sleep phenotypes.

A. Wyss, Michael Brown, Xiang Li et al. · Sleep · 0 citations