Author

Xiu-Wu Bian

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Sep 2026

A Metabolic Nanoplatform Potentiates Triple-Negative Breast Cancer Radiosensitivity via Disrupting Carbonic Anhydrase IX/Pentose Phosphate Pathway Crosstalk

Radiotherapy resistance in tumors driven by metabolic adaptations within acidic microenvironments involves the upregulation of both carbonic anhydrase IX (CA IX) and the pentose phosphate pathway (PPP) as well as the functional crosstalk between them. To overcome this, we developed a polyvinylpyrrolidone (PVP)-modifi...

Zhi-Li Ma, Bin Zhao, Yun Wang et al. · ACS Nano · 0 citations

Review Open access Sep 2026

Emerging advances in multimodal AI in cancer immunotherapy: from multi-scale data integration to clinical decision support.

Immunotherapy is increasingly reshaping the therapeutic landscape of clinical oncology by inducing effective tumor regression and durable responses in various types of human cancers. However, a substantial fraction of patients resist immunotherapy, or even experience relapse after an initial response. Clinically, the c...

Wen-Jie Zhang, Ze-Yu Luo, Kai-Wen Liu et al. · Science Bulletin · 0 citations