Xiu-Ya Ren

VWA2 fuels colon cancer growth and immune evasion through Wnt/β-catenin signaling

Summary Colon adenocarcinoma (COAD) progression involves complex interactions between tumor cell intrinsic pathways and immune evasion. Here, we show that VWA2 is markedly upregulated in COAD and correlates with poor prognosis across multiple cancer types. Using patient-derived data, cell-based assays, and in vivo mode...