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Review Open access Aug 2026

The Emerging Role of UCHL1 in Neurological and Musculoskeletal Diseases

Ubiquitin C‐terminal hydrolase L1 (UCHL1) is a highly conserved deubiquitinating enzyme that has transitioned from being viewed as a “brain‐specific” protein to a global regulator of cellular proteostasis and signal transduction. As a key component of the ubiquitin‐proteasome system (UPS), UCHL1 maintains the intracell...

Ru Feng, Xiu Zhong, Jianjun Li et al. · 0 citations

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