Aug 2026
Engineered mesenchymal stem cells regulate integrated stress response for fibrosis therapy.
BACKGROUND Pulmonary fibrosis is a fatal disease with limited therapeutic options. Aberrant activation of the integrated stress response (ISR) disrupts proteostasis and promotes fibrogenesis, yet effective strategies for targeted ISR regulation in fibrotic diseases remain insufficiently explored. METHODS Here, we eng...
Jie Yu, Shu-Hua Yin, Jiong Li et al.
· i Medicina · 0 citations