A conserved alphaherpesvirus UL20 homolog is required for cytoplasmic virion maturation and secondary envelopment of Marek's disease virus.
Marek's disease virus (MDV), an oncogenic alphaherpesvirus, induces severe immunosuppression and T-cell lymphomas in chickens, posing a major threat to poultry production. Viral morphogenesis in alphaherpesviruses depends on coordinated membrane remodeling processes mediated by conserved viral membrane proteins. Althou...