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Xixi Hou

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Open access Jul 2026

Synthesis and in vitro antiproliferative activity of dolutegravir derivatives against hepatocellular carcinoma via apoptosis-related mechanisms

It is demonstrated that dolutegravir-based 1,2,3-triazole derivatives possess promising anti-hepatocellular carcinoma activity and identify compound 3b as a potential lead candidate for further anticancer drug development.

Xixi Hou, Mengmeng Huang, Qingqing Zhang et al. · RSC Advances · 0 citations