Targeting the V-ATPase A Subunit in Phytophthora sojae: Discovery of Compound A15.
Phytophthora sojae poses a major threat to global soybean production. Here, CRISPR/Cas9-mediated promoter replacement revealed that the V-ATPase A subunit gene (PsVHA-A) plays an important role in the growth, development, and pathogenicity of P. sojae, highlighting its potential as a molecular target. Using this target...