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Open access Sep 2026

Lactiplantibacillus plantarum Lp05 ensures immune developmental safety and protects against colitis via promoting Treg differentiation in mice

ABSTRACT Lactiplantibacillus plantarum (formerly Lactobacillus plantarum) Lp05, a strain isolated from pickled vegetables, is widely used as a probiotic in the food industry. However, its impact on the host immune system, especially the adaptive immune system, remains poorly understood. In this study, we systematically...

Sheng-Ning Liang, Yan-Jie Chen, Yi-Xiang Zhang et al. · 0 citations
Review Open access Aug 2026

Targeting the metabolic dependencies of tumor-associated macrophages for cancer immunotherapy

Tumor-associated macrophages (TAMs) play a pivotal role in tumor progression and immune evasion, with recent evidence indicating that metabolic reprogramming is crucial in determining their functional phenotype. Alterations in glucose, amino acid, and lipid metabolism are central to the regulation of TAMs plasticity,...

Wei-Feng Yuan, Yi-Ran Zhu, Yu-Xin Zhang et al. · 0 citations

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