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Xu-Chang Zhou

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Open access Aug 2026

Glucose-Independent Metabolic Signatures of SGLT2 Inhibition in Diabetic Kidney Disease: Integrated Insights from Mendelian Randomization and Transcriptomics.

Background Diabetic kidney disease (DKD) remains a major cause of terminal renal failure, with residual risk remaining unacceptably high despite standard glucose control. Although the sodium-glucose co-transporter 2 (SGLT2) inhibitors have proven reno-protective properties extending beyond that explained by glucose low...

Yang Zhou, Jie Peng, Xu-Chang Zhou et al. · 0 citations

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