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Xu-Dong Kong

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Aug 2026

Kinetic Resolution of Citronellol by an Engineered Alcohol Oxidase for the Production of (R)-Citronellal and (S)-Citronellol.

(R)-citronellal is an important intermediate for aroma compounds and pharmaceuticals. Herein, we engineered the choline oxidase, AcCO6, from Arthrobacter chlorophenolicus, to enhance enantioselective oxidation of citronellol. Through site-directed and combinatorial mutagenesis, a quadruple mutant, AcCO6_M4a (W332V/A89S...

Peng-Cen Han, Die Lu, Xiao-Mei Wu et al. · 0 citations

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