Rational Design of Stable, Dual-Functionalized Ferritin Nanocages via Molecular Dynamics-Guided In Vitro Heteromeric Assembly
This study presents a rational, simulation-guided strategy to overcome the structural instability of ferritin nanocages upon conjugation with large biomoleculesa common challenge in protein-based bioconjugates. Molecular dynamics (MD) simulations were performed using epidermal growth factor (EGF) and enhanced green...