Xu-Xu Yang

Context-dependent roles of the NLRP3 inflammasome in osteomyelitis and strategies for precision modulation

Osteomyelitis is an inflammatory bone disease caused by pathogen infection, characterized by persistent infection, bone destruction, and impaired repair. Its refractoriness stems from the interplay between pathogen persistence and dysregulated host immune responses within the unique bone microenvironment. As a critical...