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Xu-Yang Cao

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Open access Aug 2026

Dysregulated JAK2 signaling delays fracture healing by enhancing STAT3/NF-κB signaling and inhibiting BMP2-mediated osteogenesis.

These findings identify bidirectional JAK2 dysregulation as a potential mechanism linking metabolic dysfunction and sustained JAK2 activation to impaired bone regeneration andModulation of JAK2-mediated inflammatory signaling may represent a potential therapeutic approach to improve fracture repair in metabolic and hem...

Cheng Zhang, Xuebin Zhang, Yang Luo et al. · 0 citations

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