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Xu-Yun Zhou

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Open access Sep 2026

Malnutrition as an independent risk factor for fluoropyrimidine- and oxaliplatin-based chemotherapy-induced cardiovascular toxicity in colorectal cancer: a single-center retrospective cohort study

Background Fluoropyrimidine- and oxaliplatin-based regimens (FOLFOX/XELOX) are the standard of care for colorectal cancer (CRC) but carry significant cardiovascular toxicity. Malnutrition, present in up to 60% of post-surgical CRC patients, may amplify this toxicity through systemic inflammation and pharmacokinetic alt...

Xu-Yun Zhou, Biao Tang, Xiao-Mei Sheng et al. · 0 citations

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