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Author

Xu Zhang

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Oct 2026

Inhibition of mitochondrial permeability transition selectively suppresses thrombogenic platelet procoagulant activity.

Platelets support coagulation by externalizing phosphatidylserine (PS), creating a catalytic surface for thrombin generation and fibrin formation. Although platelet PS exposure is required for hemostasis, excessive procoagulant platelet activity drives thrombosis. Sustained calcium influx after strong agonist stimulati...

Yi-Heng Zhang, Jordan Sandler, O. Owegie et al. · 0 citations

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