Author

Xu-Zhao Li

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Open access Aug 2026

Arylsulfatase D promotes malignant phenotypes in glioblastoma cells and is linked to altered Hippo pathway phosphorylation

Introduction Glioblastoma (GBM) is a highly aggressive malignant brain tumor with persistently poor clinical outcomes and few effective treatment options. Arylsulfatase D (ARSD), a lysosomal sulfatase implicated in several cancers, has not been fully characterized in GBM. Methods ARSD expression in GBM was evaluated us...

Xu-Zhao Li, Qi-Fan Hou, Yan-Li Tang et al. · Frontiers in Oncology · 0 citations

Review Open access Sep 2026

The nociceptor-CGRP-lactate axis in cancer immune escape: linking neural signaling, immunometabolism, and immunotherapy resistance.

Cancer neuroscience has expanded the conceptual landscape of tumor biology by revealing that nerves are not passive bystanders within malignant tissues, but active regulators of tumor progression, immune surveillance, and therapeutic response. Among neural components of the tumor microenvironment, nociceptive sensory n...

Peng-Yu Zhao, Kun Wu, Zi-Xiang Jin et al. · Pharmacological Research · 0 citations