Xu-Zhuo Chen

Surface-Engineered Mitochondrial Extracellular Vesicles for Enhanced Endosomal Escape and Alleviation of Osteoarthritis-Associated Neuropathic Pain.

Mitochondrial transfer has emerged as a promising therapeutic strategy for disease driven by neural and pain-related pathologies. However, inefficient intracellular delivery and severe lysosomal degradation significantly limit its translational potential. Given the critical role of mitochondrial dysfunction in Schwann...