Xuan-Bi Mo

Dual pH/glucose-responsive berberine-loaded bioactive glass/carboxymethyl chitosan hydrogel for promoting diabetic wound healing.

Diabetic wounds are characterized by a complex pathological microenvironment involving hyperglycemia-induced oxidative stress, persistent inflammation, bacterial infection and impaired matrix remodeling. In this study, we developed BBGgel, an injectable pH- and glucose-responsive carboxymethyl chitosan/genipin hydrogel...