Author

Xuan Wang

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Open access Aug 2026

Associations of loneliness, social isolation and healthy lifestyle with life expectancy free of major physical disease and mental disorder

Loneliness and social isolation are linked to higher risks of mortality and a range of adverse physical diseases and mental disorders, yet the extent to which they affect overall health and quality of life remains unclear. Here we show that loneliness and social isolation are more strongly associated with life expectan...

Xuan Wang, Hao Ma, Yoriko Heianza et al. · Nature Communications · 0 citations

Open access Sep 2026

Blood Metabolomic Signatures of One-Hour Glucose Predict Cardiometabolic Risk

Background: Elevated 1-hour glucose levels during an oral glucose tolerance test (OGTT) strongly predict type 2 diabetes (T2D) and cardiovascular disease. We investigated whether fasting blood metabolome predicting 1-hour glucose could be a target for improving β-cell function, long-term glycemic trajectories, and redu...

Yoriko Heianza, Ming-Hao Kou, Xuan Wang et al. · Circulation Research · 0 citations