Triple-negative breast cancer (TNBC) is characterized by high metastatic potential, frequent recurrence and limited targeted regimens. The chemokine network acts as a central orchestrator, reshaping its tumor immune microenvironment (TIME) and determining therapeutic responsiveness. Yet its clinical translation remains...
Wanyu Wang, Linhua Chen, Wei Guo et al.· Frontiers in Immunology· 0 citations
A conceptual framework for developmental hazard assessment is outlined, in which exposure-window characterization, congener-specific toxicokinetics, human-relevant models, multi-omics biomarkers, and PBPK/PBTK modeling are positioned as complementary components rather than as a fully operational assessment system.
Bin Deng, Xuan Xia, Xiaoxiang Sun· Frontiers in Public Health· 0 citations
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