Xuan Yao

HDOCK-Multimer: integrating docking and combinatorial assembly for structure prediction of large protein complexes

Deep learning methods, such as AlphaFold and RosettaFold, achieve high accuracy in protein structure prediction. However, predicting the structure of large protein complexes remains challenging due to their large size and intricate multi-chain interactions. Docking-based methods can handle large proteins, but are limit...