Author

Xuan-Yao Liu

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Open access Aug 2026

Cell-type-specific eQTLs underlie the genetic architecture of complex traits.

This work unbiasedly characterized cell-type-specific eQTLs by applying a variance component model to population-scale single-cell RNA-sequencing (RNA-seq) data and established eQTL cell-type specificity as a key feature of gene regulation and partly explain why known eQTLs are depleted in gene regulatory effects on co...

Minhui Chen, Xin-Pei Wang, Lena Krockenberger et al. · Nature · 1 citation