Open access
Sep 2026
PINK1–Associated Mitophagy Protects Against Cisplatin–Induced Ototoxicity by Regulating the Subcellular Distribution of ACSL4
Cisplatin–induced ototoxicity is a significant clinical issue linked to ferroptosis and mitophagy dysfunction. This study investigated how mitophagy regulates ferroptosis in cisplatin–induced hearing loss using cultured primary rat cochlear marginal cells in vitro and a C57BL/6J mouse model of cisplatin–induced ototoxi...
Ting Li, Wen-Ting Yu, Huan-Zhi Wan et al.
· Cells · 0 citations