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Xue-Dou Lu

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Open access Sep 2026

EDTP Loss of Function Impairs Longevity and Reproduction

This study presents a comprehensive genetic characterization of DJ694, a viable GAL4 enhancer-trap allele of the age-regulated gene EDTP. EDTP transcript levels are reduced in DJ694, and homozygous flies exhibit reduced reproduction and shortened lifespan in both sexes. The fertility and longevity phenotypes are recess...

Xue-Dou Lu, T. Barwell, Scott Edelman et al. · 0 citations

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