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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Xuege Yang

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Open access Oct 2026

Sestrin1 Ameliorates Senescence and Mediates the Protective Effects of Exercise Against Hepatic Abnormality in C57BL/6J Mice.

Liver aging is characterized by structural remodeling and functional decline, frequently driven by mitochondrial dysfunction and senescence-associated secretory phenotype (SASP). Sestrins (SESNs) are a family of stress-inducible proteins, among which Sestrin1 and Sestrin2 are crucial for maintaining metabolic and redox...

Xue-Ge Yang, Yu-Chen Zou, Xiu-Ru Li et al. · 0 citations
Aug 2026

Disuse-induced skeletal muscle IDO1 activation contributes to kynurenine-dependent muscle-liver crosstalk and hepatic oxidative injury.

Physical inactivity and mechanical unloading induce skeletal muscle atrophy and are associated with systemic metabolic disorders, but the molecular basis linking muscle disuse to liver injury remains unclear. Human cohort analyses (CHARLS, NHANES), a mouse hindlimb immobilization model, and multi-level in vitro systems...

Xiu-Ru Li, Jingling Peng, Ya-Ting Huang et al. · 0 citations

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