Subregion-specific input organization of prefrontal-projecting basal forebrain cholinergic neurons and weakened striatal-NBM inhibitory transmission in 5xFAD mice.
Basal forebrain cholinergic neurons regulate cortical activity and cognition and are vulnerable in Alzheimer's disease (AD). However, the upstream circuits controlling projection-defined basal forebrain cholinergic populations remain incompletely understood. Here, we used projection-specific rabies-mediated monosynapti...