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Xue-Ling Lu

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Open access Sep 2026

A Translational Fluorescence Biosensing Strategy for Species-Specific Detection of Deinagkistrodon acutus Venom Using Complementary Time-Resolved and Rapid Diagnostic Platforms

Rapid and species-specific molecular detection remains a critical unmet need in the clinical management of snakebite poisoning, particularly when the offending species is uncertain or when residual circulating venom must be quantified after antivenom administration. Here, we developed a fluorescence-enabled dual-platfo...

Zheng-Zhuang Huang, Shi-Ling Sun, Yu-Hua Tan et al. · 0 citations
Open access Sep 2026

TRPV4-linked oxidative–lysosomal stress in myocardial ischemia/reperfusion: disease-matched transcriptomics and functional analysis in OGD/R cardiomyoblasts

Background Myocardial ischemia/reperfusion (MI/R) injury involves oxidative stress, lysosomal dysfunction, and altered autophagy. TRPV4 may link Ca2+ dysregulation to these processes, but its role in lysosomal membrane permeabilization (LMP) and autophagic impairment remains unclear. Methods Three disease-matched mouse...

Jie Yang, Jin-Cheng Li, Guan-Yao Li et al. · 0 citations

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