Open access
Jul 2026
Itgb1‐Mediated Stabilization of Vimentin Alleviates Excessive Mechanical Stress‐Induced Nucleus Pulposus Cell Pyroptosis and Intervertebral Disc Degeneration via PINK1‐Parkin‐Dependent Mitophagy
A mechanotransduction pathway from mechanical stress sensing to cellular functional regulation in IDD is revealed, providing novel insights into the pathological mechanisms underlying IDD.
Xuening Liu, Fengguang Yang, Yanni Duan et al.
· Cell Proliferation · 0 citations