Xue-Yan Zhang

Synergistic inhibition of exosome secretion and PD-L1 silence via a functional supramolecular lipid nanoparticle to boost antitumor immunity.

The treatment of malignancies remains a formidable challenge, driven by the complex interplay of exosome-mediated metastasis and PD-L1-driven immune evasion. Overcoming these barriers through simultaneous modulation of both pathways represents a critical, yet unmet, need in cancer therapy. To address this, we engineer...