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Author

Xue-Yong Zhu

2 papers indexed here

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Oct 2026

Antibodies to distinct epitopes on MPXV enveloped virion provide additive and complete protection.

The continuing evolution of monkeypox virus (MPXV) clades capable of sustained human-to-human transmission poses an escalating global health risk, yet no effective therapy exists for poxvirus infection. Here, we investigate a panel of human monoclonal antibodies (mAbs), derived from an antibody library, which targets A...

Ding Zhang, R. Fantin, Xue-Yong Zhu et al. · 0 citations
Open access Aug 2026

Single-component self-assembling protein nanoparticles displaying stabilized prefusion-closed hemagglutinin trimers for influenza vaccine development

Current influenza vaccines primarily target hemagglutinin (HA), the major viral surface glycoprotein and principal determinant of neutralizing antibody (NAb) responses. However, antigenic drift and shift, together with HA’s intrinsic metastability and low-pH sensitivity, limit broad and durable vaccine protection. Here...

Yi-Nan Zhang, Xue-Yong Zhu, Keegan Braz Gomes et al. · 0 citations

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