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Xue-Yu Wang

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Open access Sep 2026

Synthesis of benzenesulfonamide derivatives reveals anti-CCSCs activity by regulating Wnt/β-catenin pathway.

BACKGROUND Colorectal cancer (CRC) has become one of the most common causes of cancer mortality worldwide. Accumulating studies suggest that the progressive up-regulation of Wnt/β-catenin signaling is a crucial hallmark of CRC, and this pathway is involved in the development and maintenance of colorectal cancer stem ce...

Xue-Yu Wang, Kai-Li Wang, Quan-Xing Zhong et al. · 0 citations
Review Sep 2026

Nitrogen-Containing Heterocycles in Antibacterial Drug Discovery: Recent Advances and Structure-Activity Relationships.

The article analyzes synthetic strategies, antibacterial activities, and structure-activity relationships for various derivatives of nitrogen-heterocyclic antibacterial agents, including pyrazole, imidazole, triazole, thiazole, indole, and quinolone to promote clinical translation of nitrogen-heterocyclic antibacterial...

Xiao-Qing Zhu, Ping Zhang, Xue-Yu Wang et al. · 0 citations

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