Although the molecular mechanisms underlying excessive acute inflammatory responses have been widely studied, safe and effective therapeutic strategies remain limited. Herein, we investigated the protective effects of Kaempferia galanga L.-derived nanovesicles (KGNVs) against acute inflammatory injury and explored thei...
Zi-Yue Li, Dandan Zhao, Zi-Qiao Li et al.· Journal of materials chemist...· 0 citations
Osteolytic bone metastasis remains difficult to treat because effective tumor eradication and bone regeneration must be achieved simultaneously. Current calcification-based strategies are constrained by their reliance on exogenous phosphate, and poor integration with controllable therapeutic modalities. Herein, we repo...
Mitochondrial localization concentrates photosensitizing molecules near redox-sensitive organelles. In this study, we investigated SPN, a mitochondria-targeted G-quadruplex (G4)-responsive ligand. Photochemical characterization confirmed that SPN generates robust light-triggered ROS and exhibits photooxidative activity...
Ya-Kun Wang, Jia-Peng Dong, Hongshan Xie et al.· Spectrochimica Acta Part A -...· 0 citations
Drug-resistant and biofilm-associated fungal infections remain difficult to treat with conventional antifungals. Antimicrobial photodynamic therapy (aPDT) uses light-activated organic photosensitizers to generate multi-target oxidative damage with spatiotemporal control. To establish how molecular design governs antifu...
Wei-Xuan He, Zi-Hao Liang, Hongshan Xie et al.· Chemical Communications· 0 citations
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