Xun-Dou Li

Targeted therapy of colon cancer with aptamer-functionalized albumin nanoparticles loaded with disulfiram

Chemotherapy remains the primary treatment for most patients with metastatic colorectal cancer (mCRC), yet its efficacy is often limited by severe adverse effects. Drug repurposing offers a promising strategy to accelerate oncology drug development. Disulfiram (DSF), a licensed anti-alcoholism agent, has demonstrated b...