Engineered Red Blood Cell-Derived Nanovesicles Functionalized with cRGD Peptide and Loaded with Acevaltrate for Targeted Ferroptosis Therapy of Triple-Negative Breast Cancer
Triple-negative breast cancer (TNBC) remains a highly aggressive breast cancer subtype with limited molecularly targeted treatment options, while acevaltrate (ACE), a natural dual-target ferroptosis inducer, is constrained by poor aqueous solubility and insufficient tumor accumulation. Here, we engineered cyclic Arg-...