Targeted Nanostructured Lipid Carriers of Erlotinib using Transferrin for Enhanced Brain Delivery in Glioblastoma: Formulation and BBD-Based Optimization
Glioblastoma is an aggressive form of brain cancer with limited treatment therapies due to the Blood-Brain Barrier (BBB), which makes it challenging for most medications to cross it and the difficulty of achieving tumour-specific targeting. Transferrin receptors (TfR) are overexpressed on endothelial cells of the b...