Oct 2026
FTO promotes human NK cell proliferation yet restricts effector functions.
Xiao-Feng Yin, Shao-Chang Zhou, Rong-Xi Pu et al.
· Acta Pharmacologica Sinica · 0 citations
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Sep 2026
Rbp-Jκ controls NK cell late maturation and migration via chromatin landscape remodeling
Significance Despite the established role of Rbp-Jκ as the master transcriptional regulator of Notch signaling, its cell-intrinsic functions in natural killer (NK) cells remain unknown. In this study, we integrate genetic ablation (Ncr1iCre × Rbp-Jκfl/fl) studies with scRNA-seq, scATAC-seq, bulk ATAC-seq, CUT&Tag, and...
Hongyan Peng, Yao Yang, Yongjie Liu et al.
· Proceedings of the National... · 0 citations