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Y. Ebuchi

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Open access Oct 2026

Systemic atherosclerosis assessment using lipoprotein(a) and angioscopy: a prospective study of cholesterol crystal detection

Non-obstructive general angioscopy (NOGA) enables direct, high-resolution visualization of the aortic intimal surface in vivo and allows real-time assessment of plaque morphology and activity. Ruptured aortic plaques (RPs) have been associated with systemic complications, including cerebral infarction, renal dysf...

Y. Tanaka, K. Kojima, K. Agune et al. · 0 citations
Open access Oct 2026

Temporal changes and treatment-associated stabilization of aortic ruptured plaques assessed by non-obstructive general angioscopy

Intensive lipid-lowering therapy reduces cardiovascular events by lowering low-density lipoprotein cholesterol (LDL-C) and stabilizing coronary vulnerable plaques in patients with coronary artery disease (CAD). Whether similar disease-modifying effects occur in ruptured plaques of the aorta remains unknown. Non-o...

K. Kojima, K. Agune, N. Kurito et al. · 0 citations
Open access Oct 2026

Aortic plaque characteristics and hypertension: insights from non-obstructive general angioscopy

The relationship between hypertension and aortic plaque instability detected by NOGA was evaluated and it was found that hypertension may contribute not only to plaque burden but also to plaque destabilization in the aorta.

K. Kojima, K. Agune, N. Kurito et al. · 0 citations
Open access Sep 2026

Association between serum lipoprotein(a) levels and aortic vulnerable plaques assessed by non-obstructive general angioscopy

Background and aims Elevated lipoprotein(a) [Lp(a)] levels are recognized as a genetic risk factor for atherosclerotic cardiovascular disease. Previous coronary imaging studies have linked elevated Lp(a) levels to vulnerable coronary plaque characteristics. However, the relationship between elevated Lp(a) levels and vu...

K. Kojima, Yudai Tanaka, Katsunori Fukumoto et al. · 0 citations

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