Acute phosphate-salt exposure is associated with attenuation of the albumin-producing phenotype, HNF4A down-regulation, and ERK activation in HepaRG cells
Hyperphosphatemia is a common complication of chronic kidney disease (CKD) and has been implicated in systemic inflammation, protein-energy wasting, anemia, and skeletal muscle wasting. Hypoalbuminemia is also frequent in CKD and is associated with poor clinical outcomes. Although CKD-associated hypoalbuminemia i...